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weekly public links (weekly)

Sun, 21 Nov 2010
  • tags: medical opensource

  • Possible health applications?

    tags: informatics data

  • tags: maps google travel

  • This is the slow food movement of the internet.

    tags: funny p2p

  • tags: placebo

    • Nearly half of the doctors polled in a 2007 survey in Chicago admitted to prescribing medications they knew were ineffective for a patient’s condition—or prescribing effective drugs in doses too low to produce actual benefit—in order to provoke a placebo response.
    • “The quality of care that placebo patients get in trials is far superior to the best insurance you get in America,”
    • Benedetti has helped design a protocol for minimizing volunteers’ expectations that he calls “open/hidden.” In standard trials, the act of taking a pill or receiving an injection activates the placebo response. In open/hidden trials, drugs and placebos are given to some test subjects in the usual way and to others at random intervals through an IV line controlled by a concealed computer. Drugs that work only when the patient knows they’re being administered are placebos themselves.
    • Assumption number one was that if a trial were managed correctly, a medication would perform as well or badly in a Phoenix hospital as in a Bangalore clinic. Potter discovered, however, that geographic location alone could determine whether a drug bested placebo or crossed the futility boundary.
    • For the first time in medical history, more than 500 drug developers, doctors, academics, and trial designers put their heads together to examine the role of the placebo effect in clinical trials and healing in general.
    • No one would pay for it
    • Placebo-activated opioids, for example, not only relieve pain; they also modulate heart rate and respiration. The neurotransmitter dopamine, when released by placebo treatment, helps improve motor function in Parkinson’s patients.
    • In one study, Benedetti found that Alzheimer’s patients with impaired cognitive function get less pain relief from analgesic drugs than normal volunteers do.
    • Like any other internal network, the placebo response has limits. It can ease the discomfort of chemotherapy, but it won’t stop the growth of tumors.
    • nocebo effect
    • For example, men taking a commonly prescribed prostate drug who were informed that the medication may cause sexual dysfunction were twice as likely to become impotent.
    • the therapeutic ritual.
  • This page contains an incredible elongated map of the whole thing.

    tags: travel usa hiking camping

Posted from Diigo. The rest of my favorite links are here.

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